Including environmental factors, our diet, lifestyle factors, and social influences. For this highly complex interaction, the term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
- Medical interventions
- Chemical contaminants
- Environmental polluants
- PM 2.5
- PM 2.10
- Endogenous hormones
- Instestinal microflora
- Lipid peroxidation
- Oxidative stress
One Research Grant of 15 000 € will be awarded annually to a research project in the field of exposome and skin.
Professor Jean Krutmann Leibniz
Research Institute for Environmental Medecine, Düsseldorf, Germany
The research project may be fundamental or clinical. Projects involving animal research will not be considered. Work may be performed at any hospital, university or other not-for-profit research institution.
The applications for the VICHY EXPOSOME GRANT will be reviewed by a jury of experts chaired by Professor Jean Krutmann (Germany) and composed of Professors Craig Elmets (USA), Haidong Kan (China), Thierry Passeron (France), Sergio Schalka (Brazil).
Applications must be typed in English. The jury cannot accept unclear applications or applications where information is missing.
It must include :
- 1The candidate's curriculum vitae (maximum 3 pages)Should contain: name, date of birth, nationality, home address, business address with telephone number and email address, education and training, current and past professional positions, list of most important publications in the past five years. No more than 3 pages.
- 2A detailed description of his or her projected researchOn 5 pages maximum:
- Specific aims
- Approach and methodology
- Project funding
- Presentation of the involved team
- 3A signed copy of the VICHY EXPOSOME GRANT conditions
The deadline for applications is December 1st, 2017. Only complete electronic files will be accepted and submitted to the Grant Jury.
The awardee will be selected in December 2017. Award funding will be disbursed to the host institution.
The money granted must be used to accomplish the described research project.
All the requested elements have to be compiled into a single PDF file and sent by E-mail only to email@example.com
The winning project from health epidemiologist, Dr Tamara Schikowski, based at the IUF Leibniz Research Institute for Environmental Medicine in Germany, will be analysing data from the German SALIA cohort of 800 women to work out whether air pollution acts synergistically with UV exposure to accelerate skin ageing.
The SALIA cohort was set up over 30 years ago, initially to investigate the effects of air pollution on lung function, inflammation and ageing in women. There were two study populations, numbering nearly 5000 in total, one from rural areas and the other from the highly industrialized Ruhr area of Germany.
A wide range of baseline health measurements were established, with questionnaires on lifestyle factors and skin factors such as sensitivity to sun or red hair. In 2006, with air pollution declining, the women were assessed again with about 800 having detailed examinations that included an intensive skin ageing assessment using the well established SCINEXA skin ageing scoring system. DNA is available from all women and frozen blood and serum for 400.
Extensive data sets exist on air pollutants in the Ruhr area for each of the study areas. Land use and traffic information sets have been used as proxies for exposure to near road pollutants and the German weather service is able to provide data on direct solar radiation and diffuse sky radiation closest to the residential address. Each of the women completed a questionnaire about sun habits, holidays abroad etc.
Helped by a statistician, the team will use their Vichy Exposome Grant to prepare the data sets and then re-analyse it, comparing the main as well as the interacting effects of pollution on skin ageing.